@article{Мінухін_Торяник_Мінухіна_Похил_Мінухін_Труфанов_Калітіна_2020, title={REGULARITIES OF MORPHOLOGICAL CHANGES IN THE ORGANS OF THE MALE URINARY AND GENITAL SYSTEM IN CASE OF CRYPTOSPORIDIOSIS (generalized research materials)}, url={https://ujmh.net/index.php/journal/article/view/36}, DOI={10.37321/UJMH.2020.1-2-13}, abstractNote={<p>The aim of the study was to investigate the structural and functional changes in the male genitourinary system in the development of cryptosporidiosis.<br>Material and methods. The study was based on biopsies and necropsies, based on histological methods.<br>Results. The article is devoted to the study of structural and functional changes in the male genitourinary system in the development of cryptosporidiosis. The authors of the study emphasize the features of the nomenclature profile of cryptosporidiosis, its low certainty, the place among modern protozoal infections. The paper draws attention to the emergence of the disease, the specifics of its clinical course, the characteristics of the most accessible and effective methodological (histological) algorithm. The publication presents data on structural and functional changes of the urethra, testicles, kidneys of children with cryptosporidiosis (proven participation of the inflammatory component, destructive processes, trophic disorders). Researchers have focused on the peculiarities of the structure of the mucous membranes of the genitourinary organs in terms of cryptosporidiosis, destruction of the epithelium, microcirculation disorders. It is assumed that the factors of influence / strengthening of the latter were the activation of lysosomal (hydrolytic) enzymes capable&nbsp;of cleaving lipid - protein complexes of membranes.<br>As a result, the opinion is expressed about the role of cryptosporidiosis in the development of male infertility.<br>Conclusions. In the case of cryptosporidiosis, the most vulnerable structures of the male genitourinary system are cells of mesenchymal origin (epithelium).<br>They are characterized by atrophy, desquamation, destructive-degenerative changes, necrosis. The destruction of the endothelial layer of microvessels leads to defects in the layers of the walls of the latter, thrombosis, the development of stasis, impaired microcirculation and trophism</p&gt;}, number={1-2}, journal={Men’s Health, Gender and Psychosomatic Medicine}, author={Мінухін, Валерій and Торяник, Інна and Мінухіна, Діана and Похил, Сергій and Мінухін, Дмитро and Труфанов, Олег and Калітіна, Світлана}, year={2020}, month={Dec.}, pages={116-123} }